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Levothyroxine therapy and serum free thyroxine and free triiodothyronine concentrations.

John M. Lee, M.D., an Australian physician, points out that any thyroid function problem should be examined in the larger context of adrenal fatigue, hormone imbalances such as estrogen dominance, nutritional deficiencies, liver dysfunction, and digestion and absorption problems. Many vitamins, minerals and amino acids are needed to convert T4 to T3, and to get T3 into the cells. Dr. Lee believes that conservatively, 40% of women in the U.S. have measurably low thyroid and as a result are suffering from fatigue, depression, cold hands and feet, dry skin and hair and many other symptoms associated with hypothyroidism (low thyroid). Dr. Lee has a unique approach to treating patients with low thyroid function and advocates using only T3 for thyroid hormone replacement, and because the use of commercially-available T3 (liothyronine) is associated with serious problems such as rapid heart rate, Dr. Lee uses a slow-release T3 and reports the therapy is successful.